TEAM

Jan studied Organic and Bioorganic Chemistry at Palacký University Olomouc, where he joined the research group of Assoc. Prof. Lucie Brulíková during his BSc studies and subsequently continued in the group throughout his MSc and PhD. He completed his doctorate in 2026, with research focused on the design and synthesis of biologically active small molecules, particularly in the field of anti-infective drug discovery.

During his PhD, Jan spent three months at the University of Antwerp, where he gained experience with the biological evaluation of compounds against bacterial and parasitic pathogens. His research interests lie at the interface of synthetic and medicinal chemistry, with a particular interest in connecting compound design with biological activity. His doctoral research and scientific development were also recognised through participation in the 2025 Lindau Nobel Laureate Meeting and, shortly after completing his PhD, by receiving third prize in the Jean-Marie Lehn Prize in Chemistry awarded by the French Embassy.

Outside the research environment, Jan enjoys strength training, travelling, and spending time with his wife and friends.

Eva studied organic chemistry at Palacký University in Olomouc. Under the supervision of Associate Professor Petr Cankař, she obtained her B.Sc., M.Sc., and Ph.D. degrees. Her laboratory work focused on nitrogenous heterocycles, particularly azopyrazoles as cyclin-dependent kinase (CDK) inhibitors. During her Ph.D. studies, she visited the University of Notre Dame in Indiana, USA. There, she completed a research internship in the laboratory of Prof. Viktor Krchňák. During this internship, she learned solid-phase synthesis techniques. In 2013, she joined his group as a postdoctoral researcher, working primarily in the Olomouc laboratory with several short-term internships at Notre Dame. Her research focused on solid-phase synthesis of various heterocycles using 2-nitrobenzenesulfonamides as advanced intermediates, spiro compounds, peptidomimetics, and iminium chemistry. In 2018, she obtained a junior GAČR grant focused on greening solid-phase synthesis. She started her maternity leave in 2021. She now has two sons and has joined the group of Associate Professor Lucie Brulíková through the "UP return grant," which focuses on developing new antimycobacterial compounds. In her free time, she enjoys spending time with her family, reading science fiction books, watching movies, and traveling.

Silvie was born and raised in the Czech Republic. She studied Biology and Chemistry at Palacký University Olomouc, where she continued with a Master's degree in Bioorganic Chemistry and Chemical Biology and is currently a PhD student in Organic and Bioorganic Chemistry.

During her studies, she gained research experience through internships at the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, where she worked in the field of bioorthogonal chemistry, and later at the Norwegian University of Science and Technology (NTNU) in Trondheim, where she gained further experience in organic synthesis and biocatalysis.

Outside of the laboratory, Silvie enjoys travelling, exploring new places and spending time with friends.

Lucie earned both her Bc and Mgr degrees in Bioorganic Chemistry from Palacký University Olomouc. Throughout her undergraduate and graduate studies, she carried out her research at the Department of Organic Chemistry within the group of doc. RNDr. Lucie Brulíková, PhD. focusing on the design and synthesis of functionalised thiazolidin-4-ones for her bachelor's and master's theses.

Alongside her core research in Olomouc, Lucie expanded her expertise through international placements. During her master's studies, she completed an Erasmus research placement at the University of Southern Denmark in Odense in the group of Prof. Poul Nielsen, working on the preparation of substituted nucleotides. She subsequently undertook a two-month research stay at the Norwegian University of Science and Technology (NTNU) in Trondheim under the supervision of Prof. Elisabeth Egholm Jacobsen, contributing to the synthesis of novel compounds intended for vaccine applications.

Currently, Lucie is continuing her academic career as a PhD student in the Brulíková group, where her research remains dedicated to the development of new thiazolidin-4-one-based antitubercular therapeutics. Outside of the research lab, she loves spending her free time with family and friends or staying active through sports, with running playing by far the biggest part.

Mayuri completed her Master’s degree in Organic Chemistry at K. J. Somaiya College of Science and Commerce, University of Mumbai. She then worked at CSIR-National Chemical Laboratory, Pune, focusing on organic synthesis, total synthesis, and electro-organic chemistry. She has now joined Palacký University Olomouc as a PhD student, where her research focuses on the synthesis of novel low-molecular-weight compounds with antimicrobial activity.